There is a guide for doxorubicin elaborated by the CPNDS 69 in which it is recommended to perform a pharmacogenetic test for the variants rs2229774 G A in the gene RARG and rs17863783 G T in the UGT1A6 4, considered of high risk for developing ACT and the variant rs7853758 in the SLC28A3 gene whose allele A is associated with a reduced risk of ACT 68, 70
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