In type I endometrioid endometrial cancer, PTEN gene silencing in conjunction with defects in DNA mismatch repair genes, as evidenced by the microsatellite instability phenotype, or mutations in the K ras and or ОІ catenin genes, are recognized major alterations, which define the progression of the normal endometrium to hyperplasia, to endometrial intraepithelial neoplasia, and then on to carcinoma
clomid 50 mg Local recurrence of breast cancer after skin sparing mastectomy following core needle biopsy case reports and review of the literature